New data suggests hormones play a bigger role in men's mental health than thought
For years, the conversation around men’s declining mental health has focused on loneliness, social isolation, economic stress, and the stigma against seeking help. While those are all important factors, new data from Hone Health suggests another potential factor: hormones.
An analysis of 3,239 men with low testosterone found that 83% of those who entered treatment with moderate depression symptoms experienced a clinically meaningful improvement in their depression scores within 12 months of starting testosterone replacement therapy (TRT). Average scores fell from 11.7 (moderately severe) to 3.9 (minimal or no depression) on the PHQ-9, a widely used depression screening tool.
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