In November 2025, the Food and Drug Administration announced that hormone therapies for menopause would no longer carry a black box warning about serious risks such as heart attack, stroke and breast cancer.
That announcement triggered an increased demand for estrogen patch prescriptions — so much so that a recent Midi Health survey of nearly 8,000 women found that 44% of the participants reported difficulty filling their prescriptions. Of those women, 34% felt the estrogen shortage was impacting their well-being.
“I’ve heard of women going to different counties and sometimes different states (to get their patches),” said Barbara Marusiak, senior director of clinical research management and regulatory science for ASU’s Edson College of Nursing and Health Innovation. “And everybody is hitting the online pharmacies, too, whether it’s Amazon or somewhere else, trying to figure out where they can get the stuff.”
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