Key Points:
- NR and NMN have the best track record with no serious adverse side effects reported in human trials.
- Boosting NAD+ does not cause cancer.
- Boosting NAD+ could potentially contribute to the survival of inflammation-inducing cells, which could be mitigated with compounds called senolytics.
Boosting NAD+ can revitalize the NAD+ levels of particular individuals, including obese and older adults. Furthermore, restoring NAD+ can bring about an assortment of benefits connected to slowing aging. But are there any downsides? The following are the potential dangers associated with NAD+ and the NAD+ precursors niacin, nicotinamide, NR (nicotinamide riboside), and NMN (nicotinamide mononucleotide).