It’s a question scientist (and families) have been grappling with for years—and one that, until recently, has been met with cautious skepticism rather than clear answers. But new research published in Cell Reports Medicine1 just discovered a promising perspective.
Using advanced Alzheimer’s mouse models alongside analyses of human brain tissue, scientists found evidence that restoring a single cellular molecule may do more than slow the disease. Under certain conditions, it appeared to reverse key features of Alzheimer’s, including cognitive decline.
The molecule is NAD⁺ (nicotinamide adenine dinucleotide), a compound central to cellular energy, DNA repair, and brain resilience. And according to this research, disruptions in NAD⁺ balance may be a defining feature of Alzheimer’s severity, one that could be modifiable under the right conditions.
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