Very low exposure to bisphenol A (BPA) can have lasting effects on health. In studies of adult rats that were exposed before birth, researchers observed long-term changes in gene activity that differed by sex. Females showed gene expression patterns typically associated with males, while males showed patterns more commonly seen in females.
These shifts were linked to females moving toward a cancer-like biological state and males toward metabolic syndrome, a condition associated with higher risks of diabetes and heart disease.
Bisphenol A is a man-made chemical with estrogen-like effects that is widely used in food packaging. Although it has been banned from many products, it is still found in some types of packaging. Measurements show that levels of BPA in many people exceed what is considered safe, and earlier research has already connected the chemical to a range of harmful health outcomes.
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